Migraines are painful headaches, often accompanied by nausea, vomiting, and sensitivity to light, noise, and odors. These throbbing headaches usually occur on only one side of the head, although the pain may spread to the other side or occur on both sides at the same time. Migraines cause changes in brain chemicals and blood vessels that register pain signals leading to headaches and other symptoms. Women are about three times more prone to migraines than men. Migraines predominate between the ages of 20 and 50, but their severity and frequency decrease with age. Migraines can also manifest in early adolescence. The risk of getting a migraine is higher if there are people in the family who have it. Migraines can be caused by food, stress, and changes in daily life.